The pervasiveness of digital technologies in daily life is fundamentally changing the way individuals access and elaborate knowledge. Individuals have to process complex information, think systematically and take decisions weighting different forms of evidence. They also have to continuously update their skills to match rapid technical change at the workplace. More fundamentally, in order to seize the new opportunities that digital technologies are opening in many areas, individuals have to develop the right set of skills to make a meaningful use of these technologies. Increasing use of digital technologies at work is raising the demand for new skills along three lines: ICT specialist skills to programme, develop applications and manage networks; ICT generic skills to use such technologies for professional purposes; and ICT complementary skills to perform new tasks associated to the use of ICTs at work, e.g.: information-processing, self-direction, problem-solving and communication. Foundation skills, digital literacies as well as social and emotional skills are crucial to enable effective use of digital technologies by all individuals in their daily lives.